Arginines 29 and 59 of elongation factor G are important for GTP hydrolysis or translocation on the ribosome
GTP hydrolysis by elongation factor G (EF-G) is essential for the translocation step in protein elongation. The low intrinsic GTPase activity of EF-G is strongly stimulated by the ribosome. Here we show that a conserved arginine, R29, of Escherichia coli EF-G is crucial for GTP hydrolysis on the rib...
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| Опубликовано в:: | EMBO J |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313957/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880458/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.13.3458 |
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