Arginines 29 and 59 of elongation factor G are important for GTP hydrolysis or translocation on the ribosome

GTP hydrolysis by elongation factor G (EF-G) is essential for the translocation step in protein elongation. The low intrinsic GTPase activity of EF-G is strongly stimulated by the ribosome. Here we show that a conserved arginine, R29, of Escherichia coli EF-G is crucial for GTP hydrolysis on the rib...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Mohr, Dagmar, Wintermeyer, Wolfgang, Rodnina, Marina V.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2000
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313957/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880458/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.13.3458
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