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Arginines 29 and 59 of elongation factor G are important for GTP hydrolysis or translocation on the ribosome

GTP hydrolysis by elongation factor G (EF-G) is essential for the translocation step in protein elongation. The low intrinsic GTPase activity of EF-G is strongly stimulated by the ribosome. Here we show that a conserved arginine, R29, of Escherichia coli EF-G is crucial for GTP hydrolysis on the rib...

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Bibliografski detalji
Glavni autori: Mohr, Dagmar, Wintermeyer, Wolfgang, Rodnina, Marina V.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC313957/
https://ncbi.nlm.nih.gov/pubmed/10880458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3458
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