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Thrombospondin-1 suppresses wound healing and granulation tissue formation in the skin of transgenic mice
The function of the endogenous angiogenesis inhibitor thrombospondin-1 (TSP-1) in tissue repair has remained controversial. We established transgenic mice with targeted overexpression of TSP-1 in the skin, using a keratin 14 expression cassette. TSP-1 transgenic mice were healthy and fertile, and di...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313956/ https://ncbi.nlm.nih.gov/pubmed/10880440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3272 |
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