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Benzisothiazolones as modulators of macrophage migration inhibitory factor

Substituted N-phenylbenzisothiazolones have been investigated as inhibitors of the tautomerase activity of the proinflammatory cytokine MIF (macrophage migration inhibitory factor). Numerous compounds were found to possess antagonist activity in the low micromolar range with the most potent being th...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Jorgensen, William L., Trofimov, Alexander, Du, Xin, Hare, Alissa A., Leng, Lin, Bucala, Richard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139435/
https://ncbi.nlm.nih.gov/pubmed/21719283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.05.127
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