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Benzisothiazolones as modulators of macrophage migration inhibitory factor
Substituted N-phenylbenzisothiazolones have been investigated as inhibitors of the tautomerase activity of the proinflammatory cytokine MIF (macrophage migration inhibitory factor). Numerous compounds were found to possess antagonist activity in the low micromolar range with the most potent being th...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139435/ https://ncbi.nlm.nih.gov/pubmed/21719283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.05.127 |
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