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Benzisothiazolones as modulators of macrophage migration inhibitory factor

Substituted N-phenylbenzisothiazolones have been investigated as inhibitors of the tautomerase activity of the proinflammatory cytokine MIF (macrophage migration inhibitory factor). Numerous compounds were found to possess antagonist activity in the low micromolar range with the most potent being th...

詳細記述

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書誌詳細
主要な著者: Jorgensen, William L., Trofimov, Alexander, Du, Xin, Hare, Alissa A., Leng, Lin, Bucala, Richard
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139435/
https://ncbi.nlm.nih.gov/pubmed/21719283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.05.127
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