Destabilization of nucleosomes by an unusual DNA conformation adopted by poly(dA)⋅poly(dT) tracts in vivo

Poly(dA)⋅poly(dT) tracts are common and often found upstream of genes in eukaryotes. It has been suggested that poly(dA)⋅poly(dT) promotes transcription in vivo by affecting nucleosome formation. On the other hand, in vitro studies show that poly(dA)⋅poly(dT) can be easily incorporated into nucleoso...

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Vydáno v:	EMBO J
Hlavní autoři:	Shimizu, Mitsuhiro, Mori, Tatsuhiro, Sakurai, Takayuki, Shindo, Heisaburo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2000
Témata:	Articles
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880448/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.13.3358
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