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Destabilization of nucleosomes by an unusual DNA conformation adopted by poly(dA)⋅poly(dT) tracts in vivo

Poly(dA)⋅poly(dT) tracts are common and often found upstream of genes in eukaryotes. It has been suggested that poly(dA)⋅poly(dT) promotes transcription in vivo by affecting nucleosome formation. On the other hand, in vitro studies show that poly(dA)⋅poly(dT) can be easily incorporated into nucleoso...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Shimizu, Mitsuhiro, Mori, Tatsuhiro, Sakurai, Takayuki, Shindo, Heisaburo
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2000
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880448/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.13.3358
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