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Poly(dA-dT) Promoter Elements Increase the Equilibrium Accessibility of Nucleosomal DNA Target Sites

Polypurine tracts are important elements of eukaryotic promoters. They are believed to somehow destabilize chromatin, but the mechanism of their action is not known. We show that incorporating an A(16) element at an end of the nucleosomal DNA and further inward destabilizes histone-DNA interactions...

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Autors principals: Anderson, J. D., Widom, J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC87046/
https://ncbi.nlm.nih.gov/pubmed/11340174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.11.3830-3839.2001
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