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Poly(dA-dT) Promoter Elements Increase the Equilibrium Accessibility of Nucleosomal DNA Target Sites

Polypurine tracts are important elements of eukaryotic promoters. They are believed to somehow destabilize chromatin, but the mechanism of their action is not known. We show that incorporating an A(16) element at an end of the nucleosomal DNA and further inward destabilizes histone-DNA interactions...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Anderson, J. D., Widom, J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87046/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11340174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.11.3830-3839.2001
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