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Poly(dA-dT) Promoter Elements Increase the Equilibrium Accessibility of Nucleosomal DNA Target Sites

Polypurine tracts are important elements of eukaryotic promoters. They are believed to somehow destabilize chromatin, but the mechanism of their action is not known. We show that incorporating an A(16) element at an end of the nucleosomal DNA and further inward destabilizes histone-DNA interactions...

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Udgivet i:Mol Cell Biol
Principais autores: Anderson, J. D., Widom, J.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87046/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11340174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.11.3830-3839.2001
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