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Destabilization of nucleosomes by an unusual DNA conformation adopted by poly(dA)⋅poly(dT) tracts in vivo
Poly(dA)⋅poly(dT) tracts are common and often found upstream of genes in eukaryotes. It has been suggested that poly(dA)⋅poly(dT) promotes transcription in vivo by affecting nucleosome formation. On the other hand, in vitro studies show that poly(dA)⋅poly(dT) can be easily incorporated into nucleoso...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313933/ https://ncbi.nlm.nih.gov/pubmed/10880448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3358 |
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