Aromatase (CYP19) promoter gene polymorphism and risk of non-viral hepatitis-related hepatocellular carcinoma

BACKGROUND: Experimental studies suggest that sex hormones may induce or promote the development of hepatocellular carcinoma (HCC). Androgens are converted to estrogens by the CYP19 gene product, aromatase. Hepatic aromatase level and activity have been shown to be markedly elevated in HCC. Aromatas...

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Autores principales: Koh, Woon-Puay, Yuan, Jian-Min, Wang, Renwei, Govindarajan, Sugantha, Oppenheimer, Rowena, Zhang, Zhen-quan, Yu, Mimi C., Ingles, Sue Ann
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138892/
https://ncbi.nlm.nih.gov/pubmed/21319151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25939
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