Genetic Polymorphisms in the Methylenetetrahydrofolate Reductase and Thymidylate Synthase Genes and Risk of Hepatocellular Carcinoma

Methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase (TYMS) are known to play a role in DNA methylation, synthesis, and repair. The genetic mutations in MTHFR and TYMS genes may have influences on their respective enzyme activities. Data on the association studies of the MTHFR and TY...

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Auteurs principaux: Yuan, Jian-Min, Lu, Shelly C., Van Den Berg, David, Govindarajan, Sugantha, Zhang, Zhen-Quan, Mato, Jose M., Yu, Mimi C.
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391240/
https://ncbi.nlm.nih.gov/pubmed/17659576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21735
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