Genetic Polymorphisms in the Methylenetetrahydrofolate Reductase and Thymidylate Synthase Genes and Risk of Hepatocellular Carcinoma

Methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase (TYMS) are known to play a role in DNA methylation, synthesis, and repair. The genetic mutations in MTHFR and TYMS genes may have influences on their respective enzyme activities. Data on the association studies of the MTHFR and TY...

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Main Authors: Yuan, Jian-Min, Lu, Shelly C., Van Den Berg, David, Govindarajan, Sugantha, Zhang, Zhen-Quan, Mato, Jose M., Yu, Mimi C.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391240/
https://ncbi.nlm.nih.gov/pubmed/17659576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21735
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