Aromatase (CYP19) promoter gene polymorphism and risk of non-viral hepatitis-related hepatocellular carcinoma

BACKGROUND: Experimental studies suggest that sex hormones may induce or promote the development of hepatocellular carcinoma (HCC). Androgens are converted to estrogens by the CYP19 gene product, aromatase. Hepatic aromatase level and activity have been shown to be markedly elevated in HCC. Aromatas...

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Hauptverfasser: Koh, Woon-Puay, Yuan, Jian-Min, Wang, Renwei, Govindarajan, Sugantha, Oppenheimer, Rowena, Zhang, Zhen-quan, Yu, Mimi C., Ingles, Sue Ann
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138892/
https://ncbi.nlm.nih.gov/pubmed/21319151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25939
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