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CD8+ T cells Regulate Bone Tumor Burden Independent of Osteoclast Resorption
Blockade of osteoclast (OC) activity efficiently decreases tumor burden and associated bone erosion in immune-compromised animals bearing human osteolytic cancers. Here we show that modulation of anti-tumor T cell responses alters tumor growth in bone regardless of OC status, using genetic and pharm...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138866/ https://ncbi.nlm.nih.gov/pubmed/21602433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3922 |
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