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Predicting the Tolerated Sequences for Proteins and Protein Interfaces Using RosettaBackrub Flexible Backbone Design

Predicting the set of sequences that are tolerated by a protein or protein interface, while maintaining a desired function, is useful for characterizing protein interaction specificity and for computationally designing sequence libraries to engineer proteins with new functions. Here we provide a gen...

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Bibliografiske detaljer
Main Authors: Smith, Colin A., Kortemme, Tanja
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138746/
https://ncbi.nlm.nih.gov/pubmed/21789164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020451
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