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Plasmacytoid dendritic cell dichotomy: identification of interferon-α producing cells as a phenotypically and functionally distinct subset
Plasmacytoid dendritic cells (pDC) produce large amounts of type I interferon in response to invading pathogens, but can also suppress immune responses and promote tolerance. Here we show that in mice these functions are attributable to two distinct pDC subsets, one of which gives rise to the other....
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138736/ https://ncbi.nlm.nih.gov/pubmed/21172865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000454 |
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