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Plasmacytoid Dendritic Cells Take Up Opsonized Antigen Leading to CD4(+) and CD8(+) T Cell Activation In Vivo

Plasmacytoid dendritic cells (pDC) are the body’s main source of IFN-α, but, unlike classical myeloid DC (myDC), they lack phagocytic activity and are generally perceived as playing only a minor role in Ag processing and presentation. We show that murine pDC, as well as myDC, express Fcγ receptors (...

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Detalhes bibliográficos
Main Authors: Björck, Pia, Beilhack, Andreas, Herman, Edward I., Negrin, Robert S., Engleman, Edgar G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884144/
https://ncbi.nlm.nih.gov/pubmed/18768834
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