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X-ray crystallography: Assessment and validation of protein-small molecule complexes for drug discovery
INTRODUCTION: Crystallography is the key initial component for structure-based and fragment-based drug design and can often generate leads that can be developed into high potency drugs. Therefore, huge sums of money are committed based on the outcome of crystallography experiments and their interpre...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138648/ https://ncbi.nlm.nih.gov/pubmed/21779303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460441.2011.585154 |
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