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X-ray crystallography: Assessment and validation of protein-small molecule complexes for drug discovery

INTRODUCTION: Crystallography is the key initial component for structure-based and fragment-based drug design and can often generate leads that can be developed into high potency drugs. Therefore, huge sums of money are committed based on the outcome of crystallography experiments and their interpre...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cooper, David R., Porebski, Przemyslaw J., Chruszcz, Maksymilian, Minor, Wladek
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138648/
https://ncbi.nlm.nih.gov/pubmed/21779303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460441.2011.585154
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