1,N(2)-Etheno-2′-deoxyguanosine Adopts the syn Conformation about the Glycosyl Bond When Mismatched with Deoxyadenosine

[Image: see text] The oligodeoxynucleotide 5′-CGCATXGAATCC-3′·5′-GGATTCAATGCG-3′ containing 1,N(2)-etheno-2′-deoxyguanosine (1,N(2)-εdG) opposite deoxyadenosine (named the 1,N(2)-εdG·dA duplex) models the mismatched adenine product associated with error-prone bypass of 1,N(2)-εdG by the Sulfolobus s...

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Main Authors: Shanmugam, Ganesh, Kozekov, Ivan D., Guengerich, F. Peter, Rizzo, Carmelo J., Stone, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2011
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138413/
https://ncbi.nlm.nih.gov/pubmed/21675798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200089v
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