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Comparison of the In Vitro Replication of the 7-(2-Oxoheptyl)-1,N(2)-etheno-2′-deoxyguanosine and 1,N(2)-Etheno-2′-deoxyguanosine Lesions by Sulfolobus solfataricus P2 DNA Polymerase IV (Dpo4)
Oligonucleotides were synthesized containing the 7-(2-oxoheptyl)-etheno-dGuo adduct, which is derived from the reaction of dGuo and the lipid peroxidation product 4-oxo-2-nonenal. The in vitro replication of 7-(2-oxoheptyl)-etheno-dGuo by the model Y-family polymerase Sulfolobus solfataricus P2 DNA...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922457/ https://ncbi.nlm.nih.gov/pubmed/20578729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100082e |
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