Dimer Interface of the Effector Domain of Non-structural Protein 1 from Influenza A Virus: AN INTERFACE WITH MULTIPLE FUNCTIONS

Non-structural protein 1 from influenza A virus, NS1A, is a key multifunctional virulence factor composed of two domains: an N-terminal double-stranded RNA (dsRNA)-binding domain and a C-terminal effector domain (ED). Isolated RNA-binding and effector domains of NS1A both exist as homodimers in solu...

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Bibliographische Detailangaben
Hauptverfasser: Aramini, James M., Ma, Li-Chung, Zhou, Ligang, Schauder, Curtis M., Hamilton, Keith, Amer, Brendan R., Mack, Timothy R., Lee, Hsiau-Wei, Ciccosanti, Colleen T., Zhao, Li, Xiao, Rong, Krug, Robert M., Montelione, Gaetano T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138300/
https://ncbi.nlm.nih.gov/pubmed/21622573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.248765
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