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Biochemical Analysis of the Canonical Model for the Mammalian Circadian Clock
The current consensus model for the circadian clock in mammals is based on a transcription-translation feedback loop. In this model, CRY and PER proteins repress their own transcription by suppressing the transactivator function of the CLOCK:BMAL1 heterodimer directly (physical model) and by facilit...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138243/ https://ncbi.nlm.nih.gov/pubmed/21613214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254680 |
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