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Species specificity of the complement inhibitor compstatin investigated by all-atom molecular dynamics simulations
The development of compounds to regulate the activation of the complement system in non-primate species is of profound interest because it can provide models for human diseases. The peptide compstatin inhibits protein C3 in primate mammals and is a potential therapeutic agent against unregulated act...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138065/ https://ncbi.nlm.nih.gov/pubmed/20589629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22780 |
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