p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation

p53 is the central member of a critical tumor suppressor pathway in virtually all tumor types, where it is silenced mainly by missense mutations. In melanoma, p53 predominantly remains wild type, thus its role has been neglected. To study the effect of p53 on melanocyte function and melanomagenesis,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Terzian, Tamara, Torchia, Enrique C., Dai, Daisy, Robinson, Steven E., Murao, Kazutoshi, Stiegmann, Regan A., Gonzalez, Victoria, Boyle, Glen M., Powell, Marianne B., Pollock, Pamela M., Lozano, Guillermina, Robinson, William A., Roop, Dennis R., Box, Neil F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137930/
https://ncbi.nlm.nih.gov/pubmed/20849464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2010.00773.x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados