Akt-RSK-S6-kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases

Receptor tyrosine kinases (RTKs) activate pathways mediated by serine/threonine (Ser/Thr) kinases such as the PI3K (phosphatidylinositol 3-kinase)-Akt pathway, the Ras-MAPK (mitogen-activated protein kinase)-RSK pathway, and the mTOR (mammalian target of rapamycin)-p70 S6 pathway that control import...

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Autors principals: Moritz, Albrecht, Li, Yu, Guo, Ailan, Villén, Judit, Wang, Yi, MacNeill, Joan, Kornhauser, Jon, Sprott, Kam, Zhou, Jing, Possemato, Anthony, Ren, Jian Min, Hornbeck, Peter, Cantley, Lewis C., Gygi, Steven P., Rush, John, Comb, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137639/
https://ncbi.nlm.nih.gov/pubmed/20736484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000998
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