Nalaganje...

Stereochemical Basis for Engineered Pyrrolysyl-tRNA Synthetase and the Efficient in Vivo Incorporation of Structurally Divergent Non-native Amino Acids

[Image: see text] Unnatural amino acids (Uaas) can be translationally incorporated into proteins in vivo using evolved tRNA/aminoacyl-tRNA synthetase (RS) pairs, affording chemistries inaccessible when restricted to the 20 natural amino acids. To date, most evolved RSs aminoacylate Uaas chemically s...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Takimoto, Jeffrey K., Dellas, Nikki, Noel, Joseph P., Wang, Lei
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2011
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137230/
https://ncbi.nlm.nih.gov/pubmed/21545173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200057a
Oznake: Označite
Brez oznak, prvi označite!