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Enriching targeted sequencing experiments for rare disease alleles

Motivation: Next-generation targeted resequencing of genome-wide association study (GWAS)-associated genomic regions is a common approach for follow-up of indirect association of common alleles. However, it is prohibitively expensive to sequence all the samples from a well-powered GWAS study with su...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Edwards, Todd L., Song, Zhuo, Li, Chun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137214/
https://ncbi.nlm.nih.gov/pubmed/21700677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr324
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