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Optimized Selection of Unrelated Subjects for Whole Genome Sequencing Studies of Rare High-Penetrance Alleles
Sequencing studies using whole-genome or exome scans are still more expensive than genome wide association studies (GWAS) on a per-subject basis. As a result, subsets of subjects from a larger study are often selected for sequencing. To perform an agnostic investigation of the entire genome, subject...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3738264/ https://ncbi.nlm.nih.gov/pubmed/22623060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21641 |
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