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Caenorhabditis elegans mutant allele identification by whole-genome sequencing
Identification of the molecular lesion in Caenorhabditis elegans mutants isolated through forward genetic screens usually involves time-consuming genetic mapping. We used Illumina deep sequencing technology to sequence a complete, mutant C. elegans genome and thus pinpointed a single-nucleotide muta...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574580/ https://ncbi.nlm.nih.gov/pubmed/18677319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1249 |
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