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Confounded by Sequencing Depth in Association Studies of Rare Alleles

Next-generation DNA sequencing technologies are facilitating large-scale association studies of rare genetic variants. The depth of the sequence read coverage is an important experimental variable in the next-generation technologies and it is a major determinant of the quality of genotype calls gene...

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Detalhes bibliográficos
Autor principal: Garner, Chad
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129358/
https://ncbi.nlm.nih.gov/pubmed/21328616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20574
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