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Comparison of genetic association strategies in the presence of rare alleles

In the quest for the missing heritability of most complex diseases, rare variants have received increased attention. Advances in large-scale sequencing have led to a shift from the common disease/common variant hypothesis to the common disease/rare variant hypothesis or have at least reopened the de...

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Bibliografiske detaljer
Main Authors: Mahachie John, Jestinah M, Cattaert, Tom, De Lobel, Lizzy, Van Lishout, François, Empain, Alain, Van Steen, Kristel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287868/
https://ncbi.nlm.nih.gov/pubmed/22373505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S32
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