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Evaluation of the Role of the Vaccinia Virus Uracil DNA Glycosylase and A20 Proteins as Intrinsic Components of the DNA Polymerase Holoenzyme

The vaccinia virus DNA polymerase is inherently distributive but acquires processivity by associating with a heterodimeric processivity factor comprised of the viral A20 and D4 proteins. D4 is also an enzymatically active uracil DNA glycosylase (UDG). The presence of an active repair protein as an e...

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Detalhes bibliográficos
Main Authors: Boyle, Kathleen A., Stanitsa, Eleni S., Greseth, Matthew D., Lindgren, Jill K., Traktman, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137046/
https://ncbi.nlm.nih.gov/pubmed/21572084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.222216
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