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Crystal Structure of the Vaccinia Virus Uracil-DNA Glycosylase in Complex with DNA

Vaccinia virus polymerase holoenzyme is composed of the DNA polymerase catalytic subunit E9 associated with its heterodimeric co-factor A20·D4 required for processive genome synthesis. Although A20 has no known enzymatic activity, D4 is an active uracil-DNA glycosylase (UNG). The presence of a repai...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Burmeister, Wim P., Tarbouriech, Nicolas, Fender, Pascal, Contesto-Richefeu, Céline, Peyrefitte, Christophe N., Iseni, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505040/
https://ncbi.nlm.nih.gov/pubmed/26045555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.648352
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