Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly

BACKGROUND: Uracil-DNA glycosylases (UDGs) catalyze excision of uracil from DNA. Vaccinia virus, which is the prototype of poxviruses, encodes a UDG (vvUDG) that is significantly different from the UDGs of other organisms in primary, secondary and tertiary structure and characteristic motifs. It ado...

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Bibliografiske detaljer
Main Authors: Schormann, Norbert, Grigorian, Alexei, Samal, Alexandra, Krishnan, Raman, DeLucas, Lawrence, Chattopadhyay, Debasish
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1936997/
https://ncbi.nlm.nih.gov/pubmed/17605817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-7-45
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