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Evaluation of the Role of the Vaccinia Virus Uracil DNA Glycosylase and A20 Proteins as Intrinsic Components of the DNA Polymerase Holoenzyme

The vaccinia virus DNA polymerase is inherently distributive but acquires processivity by associating with a heterodimeric processivity factor comprised of the viral A20 and D4 proteins. D4 is also an enzymatically active uracil DNA glycosylase (UDG). The presence of an active repair protein as an e...

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Autori principali: Boyle, Kathleen A., Stanitsa, Eleni S., Greseth, Matthew D., Lindgren, Jill K., Traktman, Paula
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137046/
https://ncbi.nlm.nih.gov/pubmed/21572084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.222216
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