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Neutrophil Elastase Acts as a Biased Agonist for Proteinase-activated Receptor-2 (PAR(2))
Human neutrophil proteinases (elastase, proteinase-3, and cathepsin-G) are released at sites of acute inflammation. We hypothesized that these inflammation-associated proteinases can affect cell signaling by targeting proteinase-activated receptor-2 (PAR(2)). The PAR family of G protein-coupled rece...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137039/ https://ncbi.nlm.nih.gov/pubmed/21576245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.201988 |
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