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High Molecular Weight Kininogen Activates B(2) Receptor Signaling Pathway in Human Vascular Endothelial Cells
The nonenzymatic cofactor high molecular weight kininogen (HK) is a precursor of bradykinin (BK). The production of BK from HK by plasma kallikrein has been implicated in the pathogenesis of inflammation and vascular injury. However, the functional role of HK in the absence of prekallikrein (PK), th...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137031/ https://ncbi.nlm.nih.gov/pubmed/21586566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211557 |
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