The antiangiogenic activity of cleaved high molecular weight kininogen is mediated through binding to endothelial cell tropomyosin

Conformationally altered proteins and protein fragments derived from the extracellular matrix and hemostatic system may function as naturally occurring angiogenesis inhibitors. One example of such a protein is cleaved high molecular weight kininogen (HKa). HKa inhibits angiogenesis by inducing apopt...

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Detalhes bibliográficos
Main Authors: Zhang, Jing-Chuan, Doñate, Fernando, Qi, Xiaoping, Ziats, Nicholas P., Juarez, Jose C., Mazar, Andrew P., Pang, Yuan-Ping, McCrae, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129426/
https://ncbi.nlm.nih.gov/pubmed/12196635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192668299
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