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Cleaved high molecular weight kininogen accelerates the onset of endothelial progenitor cell senescence by induction of reactive oxygen species
OBJECTIVE: Cleaved high molecular weight kininogen (HKa), an activation product of the plasma kallikrein-kinin system, inhibits endothelial cell functions. We questioned whether HKa affects the function of endothelial progenitor cells (EPCs) and accelerates their senescence. METHODS AND RESULTS: Tre...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3089907/ https://ncbi.nlm.nih.gov/pubmed/21252071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.222430 |
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