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High Molecular Weight Kininogen Activates B(2) Receptor Signaling Pathway in Human Vascular Endothelial Cells

The nonenzymatic cofactor high molecular weight kininogen (HK) is a precursor of bradykinin (BK). The production of BK from HK by plasma kallikrein has been implicated in the pathogenesis of inflammation and vascular injury. However, the functional role of HK in the absence of prekallikrein (PK), th...

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Detalhes bibliográficos
Main Authors: Kolte, Dhaval, Osman, Noah, Yang, Jia, Shariat-Madar, Zia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137031/
https://ncbi.nlm.nih.gov/pubmed/21586566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211557
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