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Ferritin blocks inhibitory effects of two-chain high molecular weight kininogen (HKa) on adhesion and survival signaling in endothelial cells.

Angiogenesis is tightly regulated through complex crosstalk between pro- and anti-angiogenic signals. High molecular weight kininogen (HK) is an endogenous protein that is proteolytically cleaved in plasma and on endothelial cell surfaces to HKa, an anti-angiogenic protein. Ferritin binds to HKa and...

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Bibliografski detalji
Glavni autori: Lia Tesfay, Annissa J Huhn, Heather Hatcher, Frank M Torti, Suzy V Torti
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2012-01-01
Serija:PLoS ONE
Online pristup:http://europepmc.org/articles/PMC3388046?pdf=render
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