Airway Fibroblasts in Asthma Manifest an Invasive Phenotype

Rationale: Invasive cell phenotypes have been demonstrated in malignant transformation, but not in other diseases, such as asthma. Cellular invasiveness is thought to be mediated by transforming growth factor (TGF)-β1 and matrix metalloproteinases (MMPs). IL-13 is a key T(H)2 cytokine that directs m...

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Bibliographische Detailangaben
Hauptverfasser: Ingram, Jennifer L., Huggins, Molly J., Church, Tony D., Li, Yuejuan, Francisco, Dave C., Degan, Simone, Firszt, Rafael, Beaver, Denise M., Lugogo, Njira L., Wang, Ying, Sunday, Mary E., Noble, Paul W., Kraft, Monica
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2011
Schlagworte:
A. Asthma and Allergy
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136991/
https://ncbi.nlm.nih.gov/pubmed/21471104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201009-1452OC
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