Airway Fibroblasts in Asthma Manifest an Invasive Phenotype

Rationale: Invasive cell phenotypes have been demonstrated in malignant transformation, but not in other diseases, such as asthma. Cellular invasiveness is thought to be mediated by transforming growth factor (TGF)-β1 and matrix metalloproteinases (MMPs). IL-13 is a key T(H)2 cytokine that directs m...

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Autori principali: Ingram, Jennifer L., Huggins, Molly J., Church, Tony D., Li, Yuejuan, Francisco, Dave C., Degan, Simone, Firszt, Rafael, Beaver, Denise M., Lugogo, Njira L., Wang, Ying, Sunday, Mary E., Noble, Paul W., Kraft, Monica
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2011
Soggetti:
A. Asthma and Allergy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136991/
https://ncbi.nlm.nih.gov/pubmed/21471104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201009-1452OC
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