Role of Matrix Metalloproteinases-1 and -2 in Interleukin-13–Suppressed Elastin in Airway Fibroblasts in Asthma

Elastin synthesis and degradation in the airway and lung parenchyma contribute to airway mechanics, including airway patency and elastic recoil. IL-13 mediates many features of asthma pathobiology, including airway remodeling, but the effects of IL-13 on elastin architecture in the airway wall are n...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Ingram, Jennifer L., Slade, David, Church, Tony D., Francisco, Dave, Heck, Karissa, Sigmon, R. Wesley, Ghio, Michael, Murillo, Anays, Firszt, Rafael, Lugogo, Njira L., Que, Loretta, Sunday, Mary E., Kraft, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742923/
https://ncbi.nlm.nih.gov/pubmed/26074138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0290OC
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