Airway Fibroblasts in Asthma Manifest an Invasive Phenotype

Rationale: Invasive cell phenotypes have been demonstrated in malignant transformation, but not in other diseases, such as asthma. Cellular invasiveness is thought to be mediated by transforming growth factor (TGF)-β1 and matrix metalloproteinases (MMPs). IL-13 is a key T(H)2 cytokine that directs m...

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Detalhes bibliográficos
Main Authors: Ingram, Jennifer L., Huggins, Molly J., Church, Tony D., Li, Yuejuan, Francisco, Dave C., Degan, Simone, Firszt, Rafael, Beaver, Denise M., Lugogo, Njira L., Wang, Ying, Sunday, Mary E., Noble, Paul W., Kraft, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
Assuntos:
A. Asthma and Allergy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136991/
https://ncbi.nlm.nih.gov/pubmed/21471104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201009-1452OC
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