Role of Matrix Metalloproteinases-1 and -2 in Interleukin-13–Suppressed Elastin in Airway Fibroblasts in Asthma

Elastin synthesis and degradation in the airway and lung parenchyma contribute to airway mechanics, including airway patency and elastic recoil. IL-13 mediates many features of asthma pathobiology, including airway remodeling, but the effects of IL-13 on elastin architecture in the airway wall are n...

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Dades bibliogràfiques
Publicat a:Am J Respir Cell Mol Biol
Autors principals: Ingram, Jennifer L., Slade, David, Church, Tony D., Francisco, Dave, Heck, Karissa, Sigmon, R. Wesley, Ghio, Michael, Murillo, Anays, Firszt, Rafael, Lugogo, Njira L., Que, Loretta, Sunday, Mary E., Kraft, Monica
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2016
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742923/
https://ncbi.nlm.nih.gov/pubmed/26074138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0290OC
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