Lataa...
Mechanisms Underlying the Cellular Clearance of Antitrypsin Z: Lessons from Yeast Expression Systems
The most frequent cause of α(1)-antitrypsin (here referred to as AT) deficiency is homozygosity for the AT-Z allele, which encodes AT-Z. Such individuals are at increased risk for liver disease due to the accumulation of aggregation-prone AT-Z in the endoplasmic reticulum of hepatocytes. However, th...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Thoracic Society
2010
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136956/ https://ncbi.nlm.nih.gov/pubmed/21030514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.201001-007AW |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|